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What Is 7-KETO™ DHEA?

7-KETO™ DHEA, a safe and natural metabolite of DHEA, was the subject of research for over a decade at the University of Wisconsin in Madison. Of over 150 DHEA compounds tested, 7-KETO proved to be the most promising form. Researchers discovered that 7-KETO does not convert to testosterone or estrogen and supports various physiological processes.

7-KETO DHEA is also known as DHEA-Acetate-7-one or 3-acetoxy-androst-5- ene-7,17-dione.

Uses For 7-KETO™ DHEA

Metabolic Support And Weight Management: 7-KETO is several times more potent than DHEA in stimulating the thermogenic enzymes of the liver, promotes basal metabolism, and helps to increase the lean/adipose ratio. These actions safely support a leaner BMI (Body Mass Index) and healthy weight control. In a double-blind study involving 30 overweight adults, 7-KETO supported healthy body composition and BMI when combined with exercise.*

Other Patented Applications of 7-KETO™ DHEA:

Research on the role of 7-KETO in immune, cognitive and other areas of support similar to DHEA has proven promising but is preliminary.*

The Source of 7-KETO™ DHEA?

7-KETO is made from pharmaceutical grade DHEA. DHEA is produced when diosgenin is extracted from wild yam and modified in a laboratory process to achieve the final structure. Hypo-allergenic plant fiber is derived from pine cellulose.


Pure Encapsulations recommends 25-200 mg per day, in divided doses, with meals. For weight loss support, 100 mg twice daily is recommended.

Potential Side Effects Or Precautions for Using 7-KETO™ DHEA

Not to be taken by pregnant or lactating women. Vivid dreams have been reported if taken too close to bedtime. Individuals with breast, prostate, or other hormonally linked cancers (or a family history of these conditions) should avoid this product as 7-KETO has not been studied in these contexts.

Potential Drug Interactions of 7-KETO™ DHEA

7-KETO has been shown to promote healthy platelet function. As a result, it may be contraindicated for individuals using Coumadin due to a potential synergistic blood-thinning effect.


Pure Caps 7-Keto™ DHEA 100 mg.

each vegetable capsule contains DHEA-Acetate-7-one - 100 mg. (hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

Not to be taken by pregnant or lactating women.

1–2 capsules per day, in divided doses, with meals.

Pure Caps 7-Keto™ DHEA 50 mg.

each vegetable capsule contains

DHEA-Acetate-7-one - 50 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

Not to be taken by pregnant or lactating women.

1–4 capsules per day, with a meal.

Pure Caps 7-Keto™ DHEA 25 mg.

each vegetable capsule contains

DHEA-Acetate-7-one - 25 mg.

(hypo-allergenic plant fiber added to complete capsule volume requirement)

Recommended Dosage:

Not to be taken by pregnant or lactating women.

1–8 capsules per day, in divided doses, with meals.


1. Dr. John Zenk, Humanetics Corporation.

2. Zenk JL. Living Longer in the Boomer Age. Advanced Research Press, 1998.

3. Lardy H, et al. Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone. Proc Natl Acad SciUSA 1995 Jul 3;92(14):6617-9.

4. Clinical Safety and Endocrine Effects of 7-KETO DHEA. Presented at Experimental Biology 1998, April 19-22, San Francisco, CA.

5. Lardy H, et al. Ergosteroids II: Biologically active metabolites and synthetic derivatives of dehydroepiandrosterone. Steroids1998 Mar;63(3):158-65.

6. Bobyleva V et al. The effects of the ergosteroid 7-Keto DHEA on mitochondrial membrane potential: possible relationship to thermogenesis. Archives of Biochemistry and Biophysics, Vol. 341, No. 1, pp 122-128, 1997.

7. Carlon M et al. Double-Blind Study Evaluating the Effects of Exercise Plus 3-acetyl-7-oxo- dehydroepiandrosterone on Body Composition and the Endocrine System in Overweight Adults. Journal of Exercise Physiology online Vol. 2. No. 4, 1999.

8. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.  

*This is a statement of nutritional support. This statement has not been evaluated by the Food & Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

This information is for educational purposes only. Consult your physician for any health problems.

Source: Product Information Sheet from Pure Encapsulations

Manufacturers continually change product specifications. While we try our best to keep product descriptions up to date, they do not necessarily reflect the latest information available from the manufacturer. We are not responsible for incorrect or outdated product descriptions and/or images.

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