What Is Alpha-GPC?
l-Alpha-glycerophophatidylcholine (GPC-choline, alpha-GPC)
is a water-soluble phospholipid and neurotransmitter
precursor naturally occurring in the body. Unlike most
membrane phospholipids, alpha-GPC is water-soluble
because it lacks the hydrophobic tail groups.
Uses For Alpha-GPC
• Memory And Cognitive Health:
through the blood brain barrier providing a source of
choline for acetylcholine and phosphatidylcholine
biosynthesis. By supporting cell membrane fluidity and
integrity, phosphatidylcholine enhances healthy
neurotransmitter function and signal transduction.
Alpha-GPC may support healthy phospholipid turnover
in the brain, helping to counteract age-related cellular
breakdown of membrane phospholipids. Acetylcholine
is a key neurotransmitter in the brain supporting
memory and learning. Optimal phospholipid and
acetylcholine levels support cognitive, mental and
• Growth Hormone Support:
Alpha-GPC has the ability to
potentiate growth hormone releasing hormone (GHRH),
thereby supporting healthy growth hormone (GH)
levels. The mechanism of support appears to involve
increased cholinergic tone.*
Source of Alpha-GPC
Alpha-GPC is derived from highly purified soy lecithin.
Vitamin C (ascorbyl palmitate) is derived from corn
dextrose fermentation. Hypo-allergenic plant fiber is
derived from pine cellulose. There is no detectable GMO
material in this product.
Potential Side Effects Or Precautions - Alpha-GPC
If pregnant or lactating, consult your physician before
taking this product. May cause some gastrointestinal
irritation, headache or insomnia in a small percentage
Potential Drug Interactions - Alpha-GPC
At this time, there are no known adverse reactions when
taken in conjunction with medications.
Ingredients and Dosage:
each vegetable capsule of Alpha-GPC contains
stabilized alpha-GPC (L-alpha-glycerophosphatidylcholine) - 400 mg.
(providing 50% L-alpha-glycerophosphatidylcholine) - 200 mg.
vitamin C (as ascorbyl palmitate) - 20
(hypo-allergenic plant fiber added to complete capsule volume requirement)
other ingredients: calcium phosphate, silicon dioxide
3 capsules per day, in divided doses, with or between meals.
1. P M Kidd. Phospholipids: Versatile Nutraceutical Ingredients For
Functional Foods. Functional Foods and Nutraceuticals. December 2002.
2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, Meli M, Panzarasa R.
alpha-Glycerophosphocholine in the mental recovery of cerebral ischemic
attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994 Jun
3.Parnetti L, Abate G, Bartorelli L, Cucinotta D, Cuzzupoli M, Maggioni M,
Villardita C, Senin U. Multicentre study of l-alpha-glyceryl-phosphorylcholine
vs ST200 among patients with probable senile dementia of
Alzheimer's type. Drugs Aging 1993 Mar-Apr;3(2):159-64.
4.Ceda GP, Ceresini G, Denti L, Marzani G, Piovani E, Banchini A, Tarditi E,
Valenti G. alpha-Glycerylphosphorylcholine administration increases the GH
responses to GHRH of young and elderly subjects. Horm Metab Res 1992
5. Healthnotes Clinical Essentials. Copyright 2004. Healthnotes, Inc.
*This is a statement of nutritional support. This statement has not been
evaluated by the Food & Drug Administration. This product is not intended to
diagnose, treat, cure or prevent any disease.
This information is for educational purposes only. Consult your physician for
any health problems.
Source: Product Information Sheet from Pure Encapsulations
Manufacturers continually change product
specifications. While we try our best to keep product descriptions up to date,
they do not necessarily reflect the latest information available from the
manufacturer. We are not responsible for incorrect or outdated product
descriptions and/or images.
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